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Modulating autophagic flux via ROS-responsive targeted micelles to restore neuronal proteostasis in Alzheimer's disease

Compromised autophagy and defective lysosomal clearance significantly contribute to impaired neuronal proteostasis, which represents a hallmark of Alzheimer's disease (AD) and other age-related neurodegenerative disorders. Growing evidence has implicated that modulating autophagic flux, instead...

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Detalles Bibliográficos
Autores principales:	Xu, Shuting, Yang, Peng, Qian, Kang, Li, Yixian, Guo, Qian, Wang, Pengzhen, Meng, Ran, Wu, Jing, Cao, Jinxu, Cheng, Yunlong, Xu, Minjun, Zhang, Qizhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	KeAi Publishing 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668445/ https://www.ncbi.nlm.nih.gov/pubmed/34977433 http://dx.doi.org/10.1016/j.bioactmat.2021.09.017

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