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Network-based identification of miRNAs and transcription factors and in silico drug screening targeting δ-secretase involved in Alzheimer's disease

BACKGROUND: System medicine approaches have played a pivotal role in identifying novel disease networks especially in miRNA research. It is no wonder that miRNAs are implicated in multiple clinical conditions, allowing us to establish the hubs and nodes for network models of Alzheimer's Disease...

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Detalles Bibliográficos
Autores principales: Iqbal, Saleem, Malik, Md. Zubbair, Pal, Debnath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668832/
https://www.ncbi.nlm.nih.gov/pubmed/34917801
http://dx.doi.org/10.1016/j.heliyon.2021.e08502