More DNA and RNA of HBV SP1 splice variants are detected in genotypes B and C at low viral replication

HBV produces unspliced and spliced RNAs during replication. Encapsidated spliced RNA is converted into DNA generating defective virions that are detected in plasma and associated with HCC development. Herein we describe a quantitative real-time PCR detection of splice variant SP1 DNA/RNA in HBV plas...

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Detalles Bibliográficos
Autores principales: Luk, Ka-Cheung, Gersch, Jeffrey, Harris, Barbara J., Holzmayer, Vera, Mbanya, Dora, Sauleda, Silvia, Rodgers, Mary A., Cloherty, Gavin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668879/
https://www.ncbi.nlm.nih.gov/pubmed/34903774
http://dx.doi.org/10.1038/s41598-021-03304-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668879/
https://www.ncbi.nlm.nih.gov/pubmed/34903774
http://dx.doi.org/10.1038/s41598-021-03304-w

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