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An ionizable lipid toolbox for RNA delivery

Recent years have witnessed incredible growth in RNA therapeutics, which has benefited significantly from decades of research on lipid nanoparticles, specifically its key component—the ionizable lipid. This comment discusses the major ionizable lipid types, and provides perspectives for future devel...

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Detalles Bibliográficos
Autores principales: Han, Xuexiang, Zhang, Hanwen, Butowska, Kamila, Swingle, Kelsey L., Alameh, Mohamad-Gabriel, Weissman, Drew, Mitchell, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668901/
https://www.ncbi.nlm.nih.gov/pubmed/34903741
http://dx.doi.org/10.1038/s41467-021-27493-0