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An ionizable lipid toolbox for RNA delivery
Recent years have witnessed incredible growth in RNA therapeutics, which has benefited significantly from decades of research on lipid nanoparticles, specifically its key component—the ionizable lipid. This comment discusses the major ionizable lipid types, and provides perspectives for future devel...
Autores principales: | Han, Xuexiang, Zhang, Hanwen, Butowska, Kamila, Swingle, Kelsey L., Alameh, Mohamad-Gabriel, Weissman, Drew, Mitchell, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668901/ https://www.ncbi.nlm.nih.gov/pubmed/34903741 http://dx.doi.org/10.1038/s41467-021-27493-0 |
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