The BH3-only protein NOXA serves as an independent predictor of breast cancer patient survival and defines susceptibility to microtubule targeting agents

Breast cancer (BC) treatment frequently involves microtubule-targeting agents (MTAs), such as paclitaxel, that arrest cells in mitosis. Sensitivity to MTAs is defined by a subset of pro- and anti-apoptotic BCL2 family proteins controlling mitochondrial apoptosis. Here, we aimed to determine their pr...

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Detalles Bibliográficos
Autores principales: Karbon, Gerlinde, Haschka, Manuel D., Hackl, Hubert, Soratroi, Claudia, Rocamora-Reverte, Lourdes, Parson, Walther, Fiegl, Heidelinde, Villunger, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668920/
https://www.ncbi.nlm.nih.gov/pubmed/34903710
http://dx.doi.org/10.1038/s41419-021-04415-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668920/
https://www.ncbi.nlm.nih.gov/pubmed/34903710
http://dx.doi.org/10.1038/s41419-021-04415-y

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