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Cell-specific alterations in Pitx1 regulatory landscape activation caused by the loss of a single enhancer
Developmental genes are frequently controlled by multiple enhancers sharing similar specificities. As a result, deletions of such regulatory elements have often failed to reveal their full function. Here, we use the Pitx1 testbed locus to characterize in detail the regulatory and cellular identity a...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668926/ https://www.ncbi.nlm.nih.gov/pubmed/34903763 http://dx.doi.org/10.1038/s41467-021-27492-1 |