SARS-CoV-2 ferritin nanoparticle vaccine induces robust innate immune activity driving polyfunctional spike-specific T cell responses

The emergence of variants of concern, some with reduced susceptibility to COVID-19 vaccines underscores consideration for the understanding of vaccine design that optimizes induction of effective cellular and humoral immune responses. We assessed a SARS-CoV-2 spike-ferritin nanoparticle (SpFN) immun...

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Detalles Bibliográficos
Autores principales: Carmen, Joshua M., Shrivastava, Shikha, Lu, Zhongyan, Anderson, Alexander, Morrison, Elaine B., Sankhala, Rajeshwer S., Chen, Wei-Hung, Chang, William C., Bolton, Jessica S., Matyas, Gary R., Michael, Nelson L., Joyce, M. Gordon, Modjarrad, Kayvon, Currier, Jeffrey R., Bergmann-Leitner, Elke, Malloy, Allison M. W., Rao, Mangala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668928/
https://www.ncbi.nlm.nih.gov/pubmed/34903722
http://dx.doi.org/10.1038/s41541-021-00414-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668928/
https://www.ncbi.nlm.nih.gov/pubmed/34903722
http://dx.doi.org/10.1038/s41541-021-00414-4

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