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Attenuated Negative Feedback in Monocyte-Derived Macrophages From Persons Living With HIV: A Role for IKAROS

Persons living with HIV (PLWH) are at higher risk of developing secondary illnesses than their uninfected counterparts, suggestive of a dysfunctional immune system in these individuals. Upon exposure to pathogens, monocytes undergo epigenetic remodeling that results in either a trained or a tolerant...

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Detalles Bibliográficos
Autores principales: Faia, Celeste, Plaisance-Bonstaff, Karlie, Vittori, Cecilia, Wyczechowska, Dorota, Lassak, Adam, Meyaski-Schluter, Mary, Reiss, Krzysztof, Peruzzi, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668949/
https://www.ncbi.nlm.nih.gov/pubmed/34917094
http://dx.doi.org/10.3389/fimmu.2021.785905