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Short-chain aurachin D derivatives are selective inhibitors of E. coli cytochrome bd-I and bd-II oxidases

Cytochrome bd-type oxidases play a crucial role for survival of pathogenic bacteria during infection and proliferation. This role and the fact that there are no homologues in the mitochondrial respiratory chain qualify cytochrome bd as a potential antimicrobial target. However, few bd oxidase select...

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Detalles Bibliográficos
Autores principales: Radloff, Melanie, Elamri, Isam, Grund, Tamara N., Witte, Luca F., Hohmann, Katharina F., Nakagaki, Sayaka, Goojani, Hojjat G., Nasiri, Hamid, Hideto Miyoshi, Bald, Dirk, Xie, Hao, Sakamoto, Junshi, Schwalbe, Harald, Safarian, Schara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668966/
https://www.ncbi.nlm.nih.gov/pubmed/34903826
http://dx.doi.org/10.1038/s41598-021-03288-7