LncRNA RP11-295G20.2 regulates hepatocellular carcinoma cell growth and autophagy by targeting PTEN to lysosomal degradation

PTEN is a crucial tumor suppressor and loss of PTEN protein is involved in various cancers. However, the detailed molecular mechanisms of PTEN loss in cancers remain elusive, especially the involvement of lncRNAs. Here, lncRNA RP11-295G20.2 is found to be significantly upregulated in hepatocellular...

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Detalles Bibliográficos
Autores principales: Liang, Linhui, Huan, Lin, Wang, Jiajia, Wu, Yangjun, Huang, Shenglin, He, Xianghuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668967/
https://www.ncbi.nlm.nih.gov/pubmed/34903728
http://dx.doi.org/10.1038/s41421-021-00339-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668967/
https://www.ncbi.nlm.nih.gov/pubmed/34903728
http://dx.doi.org/10.1038/s41421-021-00339-1

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