An acetylation-enhanced interaction between transcription factor Sox2 and the steroid receptor coactivators facilitates Sox2 transcriptional activity and function

SRY-box 2 (Sox2) is a transcription factor with critical roles in maintaining embryonic stem (ES) cell and adult stem cell functions and in tumorigenesis. However, how Sox2 exerts its transcriptional function remains unclear. Here, we used an in vitro protein–protein interaction assay to discover tr...

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Detalles Bibliográficos
Autores principales: Huang, Yuanyong, Duan, Xiaoya, Wang, Zhen, Sun, Yimei, Guan, Qingqing, Kang, Li, Zhang, Qiao, Fang, Lan, Li, Jiwen, Wong, Jiemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668987/
https://www.ncbi.nlm.nih.gov/pubmed/34762910
http://dx.doi.org/10.1016/j.jbc.2021.101389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668987/
https://www.ncbi.nlm.nih.gov/pubmed/34762910
http://dx.doi.org/10.1016/j.jbc.2021.101389

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