Orphan cytochrome P450 20a1 CRISPR/Cas9 mutants and neurobehavioral phenotypes in zebrafish

Orphan cytochrome P450 (CYP) enzymes are those for which biological substrates and function(s) are unknown. Cytochrome P450 20A1 (CYP20A1) is the last human orphan P450 enzyme, and orthologs occur as single genes in every vertebrate genome sequenced to date. The occurrence of high levels of CYP20A1...

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Detalles Bibliográficos
Autores principales: Brun, Nadja R., Salanga, Matthew C., Mora-Zamorano, Francisco X., Lamb, David C., Goldstone, Jared V., Stegeman, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669017/
https://www.ncbi.nlm.nih.gov/pubmed/34903767
http://dx.doi.org/10.1038/s41598-021-03068-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669017/
https://www.ncbi.nlm.nih.gov/pubmed/34903767
http://dx.doi.org/10.1038/s41598-021-03068-3

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