Neuron-specific chromosomal megadomain organization is adaptive to recent retrotransposon expansions

Regulatory mechanisms associated with repeat-rich sequences and chromosomal conformations in mature neurons remain unexplored. Here, we map cell-type specific chromatin domain organization in adult mouse cerebral cortex and report strong enrichment of Endogenous Retrovirus 2 (ERV2) repeat sequences...

Descripción completa

Detalles Bibliográficos
Autores principales: Chandrasekaran, Sandhya, Espeso-Gil, Sergio, Loh, Yong-Hwee Eddie, Javidfar, Behnam, Kassim, Bibi, Zhu, Yueyan, Zhang, Yuan, Dong, Yuhao, Bicks, Lucy K., Li, Haixin, Rajarajan, Prashanth, Peter, Cyril J., Sun, Daijing, Agullo-Pascual, Esperanza, Iskhakova, Marina, Estill, Molly, Lesch, Bluma J., Shen, Li, Jiang, Yan, Akbarian, Schahram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669064/
https://www.ncbi.nlm.nih.gov/pubmed/34903713
http://dx.doi.org/10.1038/s41467-021-26862-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669064/
https://www.ncbi.nlm.nih.gov/pubmed/34903713
http://dx.doi.org/10.1038/s41467-021-26862-z

Ejemplares similares