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A protocol for macrophage depletion and reconstitution in a mouse model of sepsis

Macrophages are key innate immune cells involved in a broad spectrum of physiological and pathological processes. Macrophage depletion with clodronate-liposomes is commonly used to investigate in vivo functions of macrophages in mice. Here, we describe a protocol that combines the depletion of resid...

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Detalles Bibliográficos
Autores principales: Nguyen, Tivoli, Du, Jie, Li, Yan Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669096/
https://www.ncbi.nlm.nih.gov/pubmed/34917981
http://dx.doi.org/10.1016/j.xpro.2021.101004