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Gene-specific quantification of nascent transcription following targeted degradation of endogenous proteins in cultured cells
Genome-wide nuclear run-ons are a powerful way to determine the impact of a perturbation such as transcription factor degradation on transcriptional patterns. But often investigators are interested in monitoring transcriptional effects at specific sets of genes, rather than the entire genome. Here w...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669106/ https://www.ncbi.nlm.nih.gov/pubmed/34917979 http://dx.doi.org/10.1016/j.xpro.2021.101000 |