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Differentiation of human pluripotent stem cells into pancreatic duct-like organoids

The recapitulation of human developmental processes and pathological manifestations requires access to specific cell types and precursor stages during embryogenesis and disease. Here, we describe a scalable in vitro differentiation protocol to guide human pluripotent stem cells stepwise into pancrea...

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Detalles Bibliográficos
Autores principales: Breunig, Markus, Merkle, Jessica, Melzer, Michael Karl, Heller, Sandra, Seufferlein, Thomas, Meier, Matthias, Hohwieler, Meike, Kleger, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669107/
https://www.ncbi.nlm.nih.gov/pubmed/34917972
http://dx.doi.org/10.1016/j.xpro.2021.100913