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Kinetic Characterization of Human Histone Deacetylase 8 With Medium-Chain Fatty Acyl Lysine
Histone deacetylases (HDACs) catalyze the removal of Ɛ-acetyl-lysine residues of histones via hydrolysis. Removal of acetyl groups results in condensation of chromatin structure and alteration of gene expression by repression. HDACs are considered targets for the treatment of cancer due to their rol...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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SAGE Publications
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669121/ https://www.ncbi.nlm.nih.gov/pubmed/34917889 http://dx.doi.org/10.1177/25168657211065685 |