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Active Enhancer Assessment by H3K27ac ChIP-seq Reveals Claudin-1 as a Biomarker for Radiation Resistance in Colorectal Cancer

BACKGROUND: Colorectal cancer (CRC) represents the third most common malignant tumor in the worldwide. Radiotherapy is the common therapeutic treatment for CRC, but radiation resistance is often encountered. ChIP-seq of Histone H3K27 acetylation (H3K27ac) has revealed enhancers that play an importan...

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Detalles Bibliográficos
Autores principales: Chen, Zu-Xuan, Huang, He-Qing, Wen, Jia-Ying, Qin, Li-Sha, Song, Yao-Dong, Fang, Ye-Ying, Zeng, Da-Tong, Huang, Wei-Jian, Qin, Xin-Gan, Gan, Ting-Qing, Luo, Jie, Li, Jian-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669133/
https://www.ncbi.nlm.nih.gov/pubmed/34987334
http://dx.doi.org/10.1177/15593258211058981