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In vitro activity of a novel aminomethylcycline antibacterial (KBP-7072), a third-generation tetracycline, against clinical isolates with molecularly characterized tetracycline resistance mechanisms

OBJECTIVES: This study evaluated the in vitro activity of KBP-7072 against 413 contemporary surveillance isolates, including subsets with known tetracycline resistance genes. MATERIALS: In total, 105 Klebsiella pneumoniae (51 tetracycline resistant), 103 Escherichia coli (52 tetracycline resistant),...

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Detalles Bibliográficos
Autores principales: Pfaller, Michael A, Li, Li, Liu, Qingmei, Zhang, Jay, Huband, Michael D, Lindley, Jill M, Mendes, Rodrigo E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669227/
https://www.ncbi.nlm.nih.gov/pubmed/34917942
http://dx.doi.org/10.1093/jacamr/dlab177