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Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites
The ring-like structural maintenance of chromosomes (SMC) complex MukBEF folds the genome of Escherichia coli and related bacteria into large loops, presumably by active DNA loop extrusion. MukBEF activity within the replication terminus macrodomain is suppressed by the sequence-specific unloader Ma...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669397/ https://www.ncbi.nlm.nih.gov/pubmed/34739874 http://dx.doi.org/10.1016/j.molcel.2021.10.011 |