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Lentiviral Infections Persist in Brain despite Effective Antiretroviral Therapy and Neuroimmune Activation

HIV infection persists in different tissue reservoirs among people with HIV (PWH) despite effective antiretroviral therapy (ART). In the brain, lentiviruses replicate principally in microglia and trafficking macrophages. The impact of ART on this viral reservoir is unknown. We investigated the activ...

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Detalles Bibliográficos
Autores principales: Mohammadzadeh, Nazanin, Roda, Weston, Branton, William G., Clain, Julien, Rabezanahary, Henintsoa, Zghidi-Abouzid, Ouafa, Gelman, Benjamin B., Angel, Jonathan B., Cohen, Eric A., Gill, M. John, Li, Michael, Estaquier, Jérome, Power, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669467/
https://www.ncbi.nlm.nih.gov/pubmed/34903055
http://dx.doi.org/10.1128/mBio.02784-21