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Yeast Double Transporter Gene Deletion Library for Identification of Xenobiotic Carriers in Low or High Throughput

The routes of uptake and efflux should be considered when developing new drugs so that they can effectively address their intracellular targets. As a general rule, drugs appear to enter cells via protein carriers that normally carry nutrients or metabolites. A previously developed pipeline that sear...

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Detalles Bibliográficos
Autores principales: Almeida, Ludimila Dias, Silva, Ali Salim Faraj, Mota, Daniel Calixto, Vasconcelos, Adrielle Ayumi, Camargo, Antônio Pedro, Pires, Gabriel Silva, Furlan, Monique, Freire, Helena Martins Ribeiro da Cunha, Klippel, Angélica Hollunder, Silva, Suélen Fernandes, Zanelli, Cleslei Fernando, Carazzolle, Marcelo Falsarella, Oliver, Stephen G., Bilsland, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669479/
https://www.ncbi.nlm.nih.gov/pubmed/34903049
http://dx.doi.org/10.1128/mbio.03221-21