Combining Ivacaftor and Intensive Antibiotics Achieves Limited Clearance of Cystic Fibrosis Infections

Drugs called CFTR modulators improve the physiologic defect underlying cystic fibrosis (CF) and alleviate many disease manifestations. However, studies to date indicate that chronic lung infections that are responsible for most disease-related mortality generally persist. Here, we investigated wheth...

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Detalles Bibliográficos
Autores principales: Durfey, Samantha L., Pipavath, Sudhakar, Li, Anna, Vo, Anh T., Ratjen, Anina, Carter, Suzanne, Morgan, Sarah J., Radey, Matthew C., Grogan, Brenda, Salipante, Stephen J., Welsh, Michael J., Stoltz, David A., Goss, Christopher H., McKone, Edward F., Singh, Pradeep K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669489/
https://www.ncbi.nlm.nih.gov/pubmed/34903059
http://dx.doi.org/10.1128/mbio.03148-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669489/
https://www.ncbi.nlm.nih.gov/pubmed/34903059
http://dx.doi.org/10.1128/mbio.03148-21

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