Human Cytomegalovirus UL138 Protein Inhibits the STING Pathway and Reduces Interferon Beta mRNA Accumulation during Lytic and Latent Infections

The cGAS/STING/TBK1 (cyclic guanine monophosphate-AMP synthase/stimulator of interferon genes/Tank-binding kinase 1) innate immunity pathway is activated during human cytomegalovirus (HCMV) productive (lytic) replication in fully differentiated cells and during latency within incompletely differenti...

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Detalles Bibliográficos
Autores principales: Albright, Emily R., Mickelson, Clayton K., Kalejta, Robert F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669494/
https://www.ncbi.nlm.nih.gov/pubmed/34903048
http://dx.doi.org/10.1128/mBio.02267-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669494/
https://www.ncbi.nlm.nih.gov/pubmed/34903048
http://dx.doi.org/10.1128/mBio.02267-21

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