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Chromosome compartmentalization alterations in prostate cancer cell lines model disease progression

Prostate cancer aggressiveness and metastatic potential are influenced by gene expression and genomic aberrations, features that can be influenced by the 3D structure of chromosomes inside the nucleus. Using chromosome conformation capture (Hi-C), we conducted a systematic genome architecture compar...

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Detalles Bibliográficos
Autores principales: San Martin, Rebeca, Das, Priyojit, Dos Reis Marques, Renata, Xu, Yang, Roberts, Justin M., Sanders, Jacob T., Golloshi, Rosela, McCord, Rachel Patton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669499/
https://www.ncbi.nlm.nih.gov/pubmed/34889941
http://dx.doi.org/10.1083/jcb.202104108