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Chromosome compartmentalization alterations in prostate cancer cell lines model disease progression
Prostate cancer aggressiveness and metastatic potential are influenced by gene expression and genomic aberrations, features that can be influenced by the 3D structure of chromosomes inside the nucleus. Using chromosome conformation capture (Hi-C), we conducted a systematic genome architecture compar...
Autores principales: | San Martin, Rebeca, Das, Priyojit, Dos Reis Marques, Renata, Xu, Yang, Roberts, Justin M., Sanders, Jacob T., Golloshi, Rosela, McCord, Rachel Patton |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669499/ https://www.ncbi.nlm.nih.gov/pubmed/34889941 http://dx.doi.org/10.1083/jcb.202104108 |
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