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Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas
OBJECTIVE: Sulfonylureas, the first available drugs for the management of type 2 diabetes, remain widely prescribed today. However, there exists significant variability in glycemic response to treatment. We aimed to establish heritability of sulfonylurea response and identify genetic variants and in...
Autores principales: | Dawed, Adem Y., Yee, Sook Wah, Zhou, Kaixin, van Leeuwen, Nienke, Zhang, Yanfei, Siddiqui, Moneeza K., Etheridge, Amy, Innocenti, Federico, Xu, Fei, Li, Josephine H., Beulens, Joline W., van der Heijden, Amber A., Slieker, Roderick C., Chang, Yu-Chuan, Mercader, Josep M., Kaur, Varinderpal, Witte, John S., Lee, Ming Ta Michael, Kamatani, Yoichiro, Momozawa, Yukihide, Kubo, Michiaki, Palmer, Colin N.A., Florez, Jose C., Hedderson, Monique M., ‘t Hart, Leen M., Giacomini, Kathleen M., Pearson, Ewan R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669535/ https://www.ncbi.nlm.nih.gov/pubmed/34607834 http://dx.doi.org/10.2337/dc21-1152 |
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