SdhA blocks disruption of the Legionella-containing vacuole by hijacking the OCRL phosphatase

Legionella pneumophila grows intracellularly within a replication vacuole via action of Icm/Dot-secreted proteins. One such protein, SdhA, maintains the integrity of the vacuolar membrane, thereby preventing cytoplasmic degradation of bacteria. We show here that SdhA binds and blocks the action of O...

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Detalles Bibliográficos
Autores principales: Choi, Won Young, Kim, Seongok, Aurass, Philipp, Huo, Wenwen, Creasey, Elizabeth A., Edwards, Marc, Lowe, Martin, Isberg, Ralph R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669613/
https://www.ncbi.nlm.nih.gov/pubmed/34731604
http://dx.doi.org/10.1016/j.celrep.2021.109894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669613/
https://www.ncbi.nlm.nih.gov/pubmed/34731604
http://dx.doi.org/10.1016/j.celrep.2021.109894

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