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Analysis of a crucial interaction between the coronavirus nucleocapsid protein and the major membrane-bound subunit of the viral replicase-transcriptase complex

The coronavirus nucleocapsid (N) protein comprises two RNA-binding domains connected by a central spacer, which contains a serine- and arginine-rich (SR) region. The SR region engages the largest subunit of the viral replicase-transcriptase, nonstructural protein 3 (nsp3), in an interaction that is...

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Detalles Bibliográficos
Autores principales: Koetzner, Cheri A., Hurst-Hess, Kelley R., Kuo, Lili, Masters, Paul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669624/
https://www.ncbi.nlm.nih.gov/pubmed/34933176
http://dx.doi.org/10.1016/j.virol.2021.12.004