Comprehensive in Vitro Characterization of the LSD1 Small Molecule Inhibitor Class in Oncology

[Image: see text] Lysine-specific demethylase 1 (LSD1 or KDM1A) is a chromatin modifying enzyme playing a key role in the cell cycle and cell differentiation and proliferation through the demethylation of histones and nonhistone substrates. In addition to its enzymatic activity, LSD1 plays a fundame...

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Detalles Bibliográficos
Autores principales: Sacilotto, Natalia, Dessanti, Paola, Lufino, Michele M. P., Ortega, Alberto, Rodríguez-Gimeno, Alejandra, Salas, Jordi, Maes, Tamara, Buesa, Carlos, Mascaró, Cristina, Soliva, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669716/
https://www.ncbi.nlm.nih.gov/pubmed/34927013
http://dx.doi.org/10.1021/acsptsci.1c00223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669716/
https://www.ncbi.nlm.nih.gov/pubmed/34927013
http://dx.doi.org/10.1021/acsptsci.1c00223

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