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Comprehensive in Vitro Characterization of the LSD1 Small Molecule Inhibitor Class in Oncology
[Image: see text] Lysine-specific demethylase 1 (LSD1 or KDM1A) is a chromatin modifying enzyme playing a key role in the cell cycle and cell differentiation and proliferation through the demethylation of histones and nonhistone substrates. In addition to its enzymatic activity, LSD1 plays a fundame...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669716/ https://www.ncbi.nlm.nih.gov/pubmed/34927013 http://dx.doi.org/10.1021/acsptsci.1c00223 |