ERAP1 Controls the Interaction of the Inhibitory Receptor KIR3DL1 With HLA-B51:01 by Affecting Natural Killer Cell Function

The endoplasmic reticulum aminopeptidase ERAP1 regulates innate and adaptive immune responses by trimming peptides for presentation by major histocompatibility complex (MHC) class I molecules. Previously, we have shown that genetic or pharmacological inhibition of ERAP1 on murine and human tumor cel...

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Detalles Bibliográficos
Autores principales: D’Amico, Silvia, D’Alicandro, Valerio, Compagnone, Mirco, Tempora, Patrizia, Guida, Giusy, Romania, Paolo, Lucarini, Valeria, Melaiu, Ombretta, Falco, Michela, Algeri, Mattia, Pende, Daniela, Cifaldi, Loredana, Fruci, Doriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669763/
https://www.ncbi.nlm.nih.gov/pubmed/34917091
http://dx.doi.org/10.3389/fimmu.2021.778103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669763/
https://www.ncbi.nlm.nih.gov/pubmed/34917091
http://dx.doi.org/10.3389/fimmu.2021.778103

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