A mathematical model for the quantification of a patient’s sensitivity to checkpoint inhibitors and long-term tumour burden

A large proportion of patients with cancer are unresponsive to treatment with immune checkpoint blockade and other immunotherapies. Here, we report a mathematical model of the time-course of tumour responses to immune-checkpoint inhibitors. The model takes into account intrinsic tumour-growth rates,...

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Detalles Bibliográficos
Autores principales: Butner, Joseph D, Wang, Zhihui, Elganainy, Dalia, Al Feghali, Karine A, Plodinec, Marija, Calin, George A, Dogra, Prashant, Nizzero, Sara, Ramírez, Javier Ruiz, Martin, Geoffrey V, Tawbi, Hussein A, Chung, Caroline, Koay, Eugene J, Welsh, James W, Hong, David S, Cristini, Vittorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669771/
https://www.ncbi.nlm.nih.gov/pubmed/33398132
http://dx.doi.org/10.1038/s41551-020-00662-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669771/
https://www.ncbi.nlm.nih.gov/pubmed/33398132
http://dx.doi.org/10.1038/s41551-020-00662-0

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