Cargando…
A mathematical model for the quantification of a patient’s sensitivity to checkpoint inhibitors and long-term tumour burden
A large proportion of patients with cancer are unresponsive to treatment with immune checkpoint blockade and other immunotherapies. Here, we report a mathematical model of the time-course of tumour responses to immune-checkpoint inhibitors. The model takes into account intrinsic tumour-growth rates,...
Autores principales: | Butner, Joseph D, Wang, Zhihui, Elganainy, Dalia, Al Feghali, Karine A, Plodinec, Marija, Calin, George A, Dogra, Prashant, Nizzero, Sara, Ramírez, Javier Ruiz, Martin, Geoffrey V, Tawbi, Hussein A, Chung, Caroline, Koay, Eugene J, Welsh, James W, Hong, David S, Cristini, Vittorio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669771/ https://www.ncbi.nlm.nih.gov/pubmed/33398132 http://dx.doi.org/10.1038/s41551-020-00662-0 |
Ejemplares similares
-
Mathematical prediction of clinical outcomes in advanced cancer patients treated with checkpoint inhibitor immunotherapy
por: Butner, Joseph D., et al.
Publicado: (2020) -
Image‐guided mathematical modeling for pharmacological evaluation of nanomaterials and monoclonal antibodies
por: Dogra, Prashant, et al.
Publicado: (2020) -
Dedifferentiation-mediated stem cell niche maintenance in early-stage ductal carcinoma in situ progression: insights from a multiscale modeling study
por: Butner, Joseph D., et al.
Publicado: (2022) -
Protocol for mathematical prediction of patient response and survival to immune checkpoint inhibitor immunotherapy
por: Butner, Joseph D., et al.
Publicado: (2022) -
Mathematical modeling in cancer nanomedicine: a review
por: Dogra, Prashant, et al.
Publicado: (2019)