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Pharmacogenetics Based Dose Prediction Model for Initial Tacrolimus Dosing in Renal Transplant Recipients

Tacrolimus, an immunosuppressant used in solid organ transplantation, has a narrow therapeutic index and exhibits inter-individual pharmacokinetic variability. Achieving and maintaining a therapeutic level of the drug by giving appropriate doses is crucial for successful immunosuppression, especiall...

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Detalles Bibliográficos
Autores principales: Srinivas, Lekshmy, Gracious, Noble, Nair, Radhakrishnan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669916/
https://www.ncbi.nlm.nih.gov/pubmed/34916931
http://dx.doi.org/10.3389/fphar.2021.726784