Synergetic Effect of 4-Phenylbutyric Acid in Combination with Cyclosporine A on Cardiovascular Function in Sepsis Rats via Inhibition of Endoplasmic Reticulum Stress and Mitochondrial Permeability Transition Pore Opening

Background: Sepsis/septic shock is a common complication in the intensive care unit, and the opening of the mitochondrial permeability transition pore (mPTP), as well as the endoplasmic reticulum stress (ERS), play important roles in this situation. Whether the combination of anti-ERS and anti-mPTP...

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Detalles Bibliográficos
Autores principales: Kuang, Lei, Zhu, Yu, Wu, Yue, Peng, Xiaoyong, Tian, Kunlun, Liu, Liangming, Li, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670008/
https://www.ncbi.nlm.nih.gov/pubmed/34916944
http://dx.doi.org/10.3389/fphar.2021.770558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670008/
https://www.ncbi.nlm.nih.gov/pubmed/34916944
http://dx.doi.org/10.3389/fphar.2021.770558

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