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Cadence discovery: study protocol for a dose-finding and mechanism of action clinical trial of sodium benzoate in people with treatment-refractory schizophrenia

BACKGROUND: Schizophrenia is a persistent psychotic disorder often accompanied by severe disability and premature mortality. New pharmacological treatments are urgently needed. Sodium benzoate, a common food preservative holds potential to be an effective, accessible treatment for schizophrenia, tho...

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Detalles Bibliográficos
Autores principales: Baker, Andrea, Clarke, Lachlan, Donovan, Peter, P. J. Ungerer, Jacobus, Hartel, Gunter, Bruxner, George, Cocchi, Luca, Gordon, Anne, Moudgil, Vikas, Robinson, Gail, Roy, Digant, Sohal, Ravinder, Whittle, Emma, Scott, James G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670031/
https://www.ncbi.nlm.nih.gov/pubmed/34903265
http://dx.doi.org/10.1186/s13063-021-05890-6