Flavonoids kaempferol and quercetin are nuclear receptor 4A1 (NR4A1, Nur77) ligands and inhibit rhabdomyosarcoma cell and tumor growth

BACKGROUND: Flavonoids exhibit both chemopreventive and chemotherapeutic activity for multiple tumor types, however, their mechanisms of action are not well defined. Based on some of their functional and gene modifying activities as anticancer agents, we hypothesized that kaempferol and quercetin we...

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Detalles Bibliográficos
Autores principales: Shrestha, Rupesh, Mohankumar, Kumaravel, Martin, Greg, Hailemariam, Amanuel, Lee, Syng-ook, Jin, Un-ho, Burghardt, Robert, Safe, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670039/
https://www.ncbi.nlm.nih.gov/pubmed/34906197
http://dx.doi.org/10.1186/s13046-021-02199-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670039/
https://www.ncbi.nlm.nih.gov/pubmed/34906197
http://dx.doi.org/10.1186/s13046-021-02199-9

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