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Prevalence of germline TP53 mutation among early onset middle eastern breast cancer patients

BACKGROUND: The data on prevalence and clinical relevance of TP53 germline mutations in early onset Middle-Eastern breast cancer (BC) is limited. METHODS: We determined TP53 germline mutations in a cohort of 464 early onset BC patients from Saudi Arabia using capture sequencing based next generation...

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Detalles Bibliográficos
Autores principales: Siraj, Abdul Khalid, Masoodi, Tariq, Bu, Rong, Parvathareddy, Sandeep Kumar, Iqbal, Kaleem, Azam, Saud, Al-Rasheed, Maha, Ajarim, Dahish, Tulbah, Asma, Al-Dayel, Fouad, Al-Kuraya, Khawla Sami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670057/
https://www.ncbi.nlm.nih.gov/pubmed/34906214
http://dx.doi.org/10.1186/s13053-021-00206-w