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Estimating prevalence of human traits among populations from polygenic risk scores

The genetic basis of phenotypic variation across populations has not been well explained for most traits. Several factors may cause disparities, from variation in environments to divergent population genetic structure. We hypothesized that a population-level polygenic risk score (PRS) can explain ph...

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Detalles Bibliográficos
Autores principales: Graham, Britney E., Plotkin, Brian, Muglia, Louis, Moore, Jason H., Williams, Scott M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670062/
https://www.ncbi.nlm.nih.gov/pubmed/34903281
http://dx.doi.org/10.1186/s40246-021-00370-z