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Estimating prevalence of human traits among populations from polygenic risk scores
The genetic basis of phenotypic variation across populations has not been well explained for most traits. Several factors may cause disparities, from variation in environments to divergent population genetic structure. We hypothesized that a population-level polygenic risk score (PRS) can explain ph...
Autores principales: | Graham, Britney E., Plotkin, Brian, Muglia, Louis, Moore, Jason H., Williams, Scott M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670062/ https://www.ncbi.nlm.nih.gov/pubmed/34903281 http://dx.doi.org/10.1186/s40246-021-00370-z |
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