Blockade of glutamine-dependent cell survival augments antitumor efficacy of CPI-613 in head and neck cancer

BACKGROUND: Alterations in metabolism are one of the emerging hallmarks of cancer cells and targeting dysregulated cancer metabolism provides a new approach to developing more selective therapeutics. However, insufficient blockade critical metabolic dependencies of cancer allows the development of m...

Descripción completa

Detalles Bibliográficos
Autores principales: Lang, Liwei, Wang, Fang, Ding, Zhichun, Zhao, Xiangdong, Loveless, Reid, Xie, Jin, Shay, Chloe, Qiu, Peng, Ke, Yonggang, Saba, Nabil F., Teng, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670127/
https://www.ncbi.nlm.nih.gov/pubmed/34906193
http://dx.doi.org/10.1186/s13046-021-02207-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670127/
https://www.ncbi.nlm.nih.gov/pubmed/34906193
http://dx.doi.org/10.1186/s13046-021-02207-y

Ejemplares similares