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Distinct role of histone chaperone Asf1a and Asf1b during fertilization and pre-implantation embryonic development in mice

BACKGROUND: Asf1 is a well-conserved histone chaperone that regulates multiple cellular processes in different species. Two paralogous genes, Asf1a and Asf1b exist in mammals, but their role during fertilization and early embryogenesis remains to be investigated further. METHODS: We analyzed the dyn...

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Detalles Bibliográficos
Autores principales: Wang, Xuemei, Wang, Lu, Dou, Jie, Yu, Tianjiao, Cao, Pengbo, Fan, Na, Borjigin, Uyunbilig, Nashun, Buhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670131/
https://www.ncbi.nlm.nih.gov/pubmed/34906203
http://dx.doi.org/10.1186/s13072-021-00430-7