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gcMECM: graph clustering of mutual exclusivity of cancer mutations

BACKGROUND: Next-generation sequencing platforms allow us to sequence millions of small fragments of DNA simultaneously, revolutionizing cancer research. Sequence analysis has revealed that cancer driver genes operate across multiple intricate pathways and networks with mutations often occurring in...

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Detalles Bibliográficos
Autores principales: Hu, Ying, Yan, Chunhua, Chen, Qingrong, Meerzaman, Daoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670134/
https://www.ncbi.nlm.nih.gov/pubmed/34906079
http://dx.doi.org/10.1186/s12859-021-04505-w