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Characterization and modulation of endoplasmic reticulum stress response target genes in Kluyveromyces marxianus to improve secretory expressions of heterologous proteins

BACKGROUND: Kluyveromyces marxianus is a promising cell factory for producing bioethanol and that raised a demand for a high yield of heterologous proteins in this species. Expressions of heterologous proteins usually lead to the accumulation of misfolded or unfolded proteins in the lumen of the end...

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Detalles Bibliográficos
Autores principales: Shi, Tianfang, Zhou, Jungang, Xue, Aijuan, Lu, Hong, He, Yungang, Yu, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670139/
https://www.ncbi.nlm.nih.gov/pubmed/34906221
http://dx.doi.org/10.1186/s13068-021-02086-7