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TRIM38 triggers the uniquitination and degradation of glucose transporter type 1 (GLUT1) to restrict tumor progression in bladder cancer

BACKGROUND: Loss-of-function mutations or abnormal expressions of E ubiquitin ligases contributes to tumorigenesis. TRIM38 was reported to regulate immunity, inflammatory responses or apoptosis, but its roles in tumor progression remain inconclusive. This study aimed to investigate the functional ro...

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Detalles Bibliográficos
Autores principales: Wang, Xiaojing, He, Hongchao, Rui, Wenbin, Zhang, Ning, Zhu, Yu, Xie, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670142/
https://www.ncbi.nlm.nih.gov/pubmed/34906161
http://dx.doi.org/10.1186/s12967-021-03173-x