Efficient discovery of potential inhibitors for SARS-CoV-2 3C-like protease from herbal extracts using a native MS-based affinity-selection method

The 3C-like protease (3CLpro) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is essential to the virus life cycle and is supposed to be a potential target for the treatment of coronaviral infection. Traditional Chinese medicines (TCMs) have played an impressive role in the treatment...

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Detalles Bibliográficos
Autores principales: Zhu, Dafu, Su, Haixia, Ke, Changqiang, Tang, Chunping, Witt, Matthias, Quinn, Ronald J., Xu, Yechun, Liu, Jia, Ye, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670146/
https://www.ncbi.nlm.nih.gov/pubmed/34929567
http://dx.doi.org/10.1016/j.jpba.2021.114538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670146/
https://www.ncbi.nlm.nih.gov/pubmed/34929567
http://dx.doi.org/10.1016/j.jpba.2021.114538

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