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Molecular characterization of equine thymidine kinase 1 and preliminary evaluation of its suitability as a serum biomarker for equine lymphoma

BACKGROUND: Thymidine kinase 1 (TK1) plays a key role in the synthesis of deoxythymidine triphosphate (dTTP) and is thus important for DNA replication and cell proliferation. The expression of TK1 is highest during S-phase, and it is rapidly degraded after mitosis. In cancer cells, TK1 is upregulate...

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Detalles Bibliográficos
Autores principales: Wang, Liya, Unger, Lucia, Sharif, Hanan, Eriksson, Staffan, Gerber, Vinzenz, Rönnberg, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670147/
https://www.ncbi.nlm.nih.gov/pubmed/34906077
http://dx.doi.org/10.1186/s12860-021-00399-x