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Irinotecan/scFv co-loaded liposomes coaction on tumor cells and CAFs for enhanced colorectal cancer therapy

BACKGROUND: Cancer-associated fibroblasts (CAFs), as an important component of stroma, not only supply the “soils” to promote tumor invasion and metastasis, but also form a physical barrier to hinder the penetration of therapeutic agents. Based on this, the combinational strategy that action on both...

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Detalles Bibliográficos
Autores principales: Li, Zhaohuan, Liu, Chunxi, Li, Chenglei, Wang, Fangqing, Liu, Jianhao, Zheng, Zengjuan, Wu, Jingliang, Zhang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670172/
https://www.ncbi.nlm.nih.gov/pubmed/34906155
http://dx.doi.org/10.1186/s12951-021-01172-0